Jamie R Johnston Selected Research

Troponin C

4/2021	Anomalous structural dynamics of minimally frustrated residues in cardiac troponin C triggers hypertrophic cardiomyopathy.
1/2021	A comprehensive guide to genetic variants and post-translational modifications of cardiac troponin C.
1/2019	Familial Dilated Cardiomyopathy Associated With a Novel Combination of Compound Heterozygous TNNC1 Variants.
10/2018	Structural and functional impact of troponin C-mediated Ca2+ sensitization on myofilament lattice spacing and cross-bridge mechanics in mouse cardiac muscle.
4/2017	Myosin Rod Hypophosphorylation and CB Kinetics in Papillary Muscles from a TnC-A8V KI Mouse Model.

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Jamie R Johnston Research Topics

Disease

4	Cardiomyopathies (Cardiomyopathy) 12/2021 - 01/2018
2	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 04/2021 - 10/2018
1	Congenital Heart Defects (Congenital Heart Defect) 01/2022
1	Protein Deficiency 12/2021
1	Heart Failure 01/2021
1	Ventricular Fibrillation 01/2021
1	familial dilated cardiomyopathy 01/2019
1	Neoplasms (Cancer) 01/2018
1	Restrictive Cardiomyopathy 04/2017

Drug/Important Bio-Agent (IBA)

5	Troponin CIBA 04/2021 - 04/2017
1	DystrophinIBA 12/2021
1	Proteins (Proteins, Gene)FDA Link 04/2021
1	Lysine (L-Lysine)FDA Link 01/2021
1	Lamin Type A (Lamin A)IBA 01/2021
1	TroponinIBA 01/2018

Therapy/Procedure

1	Drug Therapy (Chemotherapy) 01/2022
1	Genomic Medicine 12/2021
1	Therapeutics 12/2021